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Descriptor English: ADP-Ribosylation Factors
Descriptor Spanish: Factores de Ribosilacion-ADP
Descriptor factores de ribosilación del ADP
Scope note: PROTEÍNAS MONOMÉRICAS DE UNIÓN AL GTP que inicialmente fueron reconocidas como activadores alostéricos de la MONO(ADP-RIBOSA) TRANSFERASA de la subunidad catalítica de la TOXINA DEL CÓLERA. Íntervienen en el tráfico de vesículas y en la activación de la FOSFOLIPASA D. Esta enzima fue clasificada antiguamente como EC 3.6.1.47.
Descriptor Portuguese: Fatores de Ribosilação do ADP
Descriptor French: Facteurs d'ADP-ribosylation
Entry term(s): ADP Ribosylation Factor
ADP Ribosylation Factors
ADP-Ribosylation Factor
ARF Protein Cofactor
Tree number(s): D08.811.277.040.330.300.400.100
D12.776.157.325.515.100
D12.776.476.338.400.100
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D020727
Scope note: MONOMERIC GTP-BINDING PROTEINS that were initially recognized as allosteric activators of the MONO(ADP-RIBOSE) TRANSFERASE of the CHOLERA TOXIN catalytic subunit. They are involved in vesicle trafficking and activation of PHOSPHOLIPASE D. This enzyme was formerly listed as EC 3.6.1.47
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.6.5.2
Previous Indexing: G-Proteins (1985-1999)
Public MeSH Note: 2000; ARF PROTEIN COFACTOR (now ADP-RIBOSYLATION FACTORS) was indexed under G-PROTEINS 1984-1999
History Note: 2000; use ADP-RIBOSYLATION FACTORS (NM) 1984-1999
DeCS ID: 34414
Unique ID: D020727
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2015/11/23
ADP-Ribosylation Factors - Preferred
Concept UI M0328150
Scope note MONOMERIC GTP-BINDING PROTEINS that were initially recognized as allosteric activators of the MONO(ADP-RIBOSE) TRANSFERASE of the CHOLERA TOXIN catalytic subunit. They are involved in vesicle trafficking and activation of PHOSPHOLIPASE D. This enzyme was formerly listed as EC 3.6.1.47
Preferred term ADP-Ribosylation Factors
Entry term(s) ADP Ribosylation Factor
ADP Ribosylation Factors
ADP-Ribosylation Factor
ARF Protein Cofactor



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